Principal Investigator
Minho University
Despite Bacterial vaginosis (BV) significant impact on women worldwide, we still do not know BV etiology. For long, two main theories attempted to describe BV: the single-agent and the polymicrobial theory. Recent developments have shed some light in BV etiology. The association of the biofilm phenotype to the clinically relevant clue cells, and the clarification of genomic diversity of Gardnerella that led to the description of 3 novel Gardnerella species on a total of 13 possible genomic species (most yet uncharacterized).
Despite more than 300 species have been found associated with BV, it is becoming evident that many are not directly involved in BV development. The existence of more Gardnerella species also casts a new light on the vaginal colonization on healthy women by non-virulent Gardnerella spp.
In this talk, I will address how specific bacterial interactions can contribute to BV development and BV treatment failure, and will point out a possible novel treatment against BV associated biofilms.
Disclosure information not submitted.
SY5.4 - Advances in BV Biofilm Research and Investigational Treatments in this Area
Wednesday, July 26, 2023
11:05 – 11:25 CST