(P248) Mycoplasma Genitalia Testing During Admission In An Urban Juvenile Detention Center 2022

Background:

Mycoplasma genitalium (Mgen) may cause asymptomatic or symptomatic urethritis (in males) and urethritis +/- cervicitis (in females). Infection may be persistent and has an association with pelvic inflammatory disease (PID) and infertility. Detained youth have high rates of sexually transmitted infections. The prevalence of Mgen among youth admitted to an urban juvenile temporary detention center (JTDC) from 01-2022 through to 12-2022 is presented.

Methods:

Descriptive analyses were performed. Demographic data - gender, age, race/ethnicity; presence of co-infection with gonorrhea, chlamydia, and or trichomonas were analyzed. Quantitative variables are expressed as percentage (%) and means (+/- standard deviation [SD]); comparison of means (SD) performed using 2-sample t-test. Data was prepared and analyzed using Microsoft Excel and Stata Version 17.

Results:

Mgen testing were performed using Nucleic Acid Amplification Testing (NAAT) with Aptima Urine Specimen Collection Kit. 363 residents were tested; 344 (95%) were males; 313 (86%) Black; 47 (13%) Hispanic; 350 (98%) identified as heterosexual; mean (±SD) age (years) was 16.3 (±1.4); mean (±SD) age of sexual debut was 13 (±2.0); mean (±SD) lifetime partners was 8.2 (±10.6); and mean (±SD) number of current partners 1.8 (±1.7). 48 (13%) tested positive for Mgen; 44 (92%) identified as heterosexuals; 16 (33%) reported some condom use. Co-infections were common - 18 (38%) with Chlamydia, 4(8%) with Gonorrhea and 2 (4%) with Trichomonas. 27(56%) tested positive for Mgen only. There was no statistically significant difference in the following for Mgen+ vs Mgen- residents: mean (±SD) age (16.5 (±0.9) v 16.2 (±1.4), p 0.16); mean (±SD) age of sexual debut (13.2 (±1.8) v 13.0 (±2.0), p 0.71); mean (±SD) number of current (2.6 (±2.3) v 1.6 (±1.4), p 0.05) and mean (±SD) lifetime partners (9.5 (±1.7) v 7.7 (±1.4), p 0.38).



Conclusion:

13% of youth in an urban JTDC had positive Mgen on routine urine NAAT testing with the majority, 27 (56%) testing positive for Mgen only. Mgen is associated with asymptomatic and persistent urethritis in men; PID and infertility in females. Findings support the consideration for routine Mgen testing in sexually active youth. Further studies are needed to determine the public health significance of routine Mgen testing.